Matrix metalloproteinase genes inXenopus development
نویسندگان
چکیده
منابع مشابه
Role of metalloproteinase matrix in development of cavity and diagnosis of pulmonary tuberculosis
Background: Matrix metalloproteases (MMPs) are multi-chain proteins that regulated by tissue inhibitor of metalloproteinases (TIMP) and several other mechanisms. This Includes transcription regulation and protein form secretion. The roles of MMPs in wound healing and tissue repair. In tuberculosis (TB), the activity of MMPs is increased and TIMP inhibitors decrease activity. Therefore, in tuber...
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MMP-11 is a key factor in physiopathological tissue remodeling. As an active form is secreted, its activity must be tightly regulated to avoid detrimental effects. Although TIMP-1 and TIMP-2 reversibly inhibit MMP-11, another more drastic scenario, presumably via hydrolysis, could be hypothesized. In this context, we have investigated the possible implication of MMP-14, since it exhibits a spat...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2004
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.20246